Reproduction Abstracts

Introduction: The sex steroid hormone progesterone (P) is the most important hormone in the canine estrous cycle for initiation and preservation of pregnancy. The responsiveness of the endometrial cells to P depends on progesterone receptors (PGRs). In recent studies alternatives to the classical progesterone receptor were identified as membrane-associated progesterone receptors (MAPGRs). Progesterone receptor membrane component-1 (PGRMC-1) is a representative of the MAPGRs wh...